ML-9 - CAS 105637-50-1

ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.

Akt, Myosin, Calcium Channel

Membrane transporter/Ion channel, Cytoskeletal Signaling, Metabolism, PI3K/Akt/mTOR signaling

105637-50-1

0.9969

C15H18Cl2N2O2S

361.29

Cl.Clc1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1

-20°C

Ice Packs

Small Compound