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Molfinity

ML216 - CAS 1430213-30-1

ML216 - CAS 1430213-30-1

SKU:MF-0018690-01

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  • Bioactivity

    ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase with an IC50 of 1.8 μM, demonstrating 28-fold selectivity against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM) .

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    1430182

  • Purity

    0.9812

  • Molecular Formula

    C15H9F4N5OS

  • Molecular Weight

    383.32

  • SMILES

    Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound