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ML218 - CAS 1346233-68-8
ML218 - CAS 1346233-68-8
SKU:MF-0006499-01
Regular price
$48.87 USD
Regular price
$33.80 USD
Sale price
$48.87 USD
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Product Details
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Bioactivity
ML218 is an orally active, selective, potent, and blood-brain barrier-crossing inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) (IC50 for Cav3.2 and Cav3.3 is 310 nM and 270 nM, respectively) .ML218 inhibits the burst activity of neurons in the subthalamic nucleus (STN) .
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Target
Calcium Channel
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Related Pathways
Membrane transporter/Ion channel, Metabolism
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CAS Number
1346233-68-8
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Purity
0.9945
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Molecular Formula
C19H26Cl2N2O
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Molecular Weight
369.33
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SMILES
[H][C@@]12CN(CCC(C)(C)C)C[C@]1([H])[C@H]2CNC(=O)c1cc(Cl)cc(Cl)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound