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Molfinity

ML289 - CAS 1382481-79-9

ML289 - CAS 1382481-79-9

SKU:MF-0016580-01

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  • Bioactivity

    ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), with over 15-fold selectivity compared to mGlu2 and no activity against mGlu5.

  • Target

    GluR

  • Related Pathways

    Neuroscience

  • CAS Number

    1382393

  • Purity

    0.9954

  • Molecular Formula

    C22H23NO3

  • Molecular Weight

    349.42

  • SMILES

    COc1ccc(cc1)C#Cc1ccc(cc1)C(=O)N1CCC[C@@H](CO)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound