ML399 - CAS 1560968-49-1

ML399 is the menin--MLL interaction inhibitor that demonstrates strong and selective effects in MLL leukemia cells, and ML399 validates a specific mechanism of action by blocking oncogenic menin-MLL signaling, providing a valuable chemical probe for functional genomics and leukemia-targeted therapeutic strategy development while enabling comprehensive mechanistic and translational hematologic cancer research.

Histone Methyltransferase

Chromatin/Epigenetic

1560918

0.982

C27H28FN3O2

445.53

[C@@](O)(C1=CC(F)=CC=C1)(C2CCN(CCCOC3=CC=C(C#N)C=C3)CC2)C4=CC=CC=N4

-20°C

Ice Packs

Small Compound