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Molfinity

MLi-2 - CAS 1627091-47-7

MLi-2 - CAS 1627091-47-7

MF-0012395-01

$49.62 USD
$34.45 USD $49.62 USD
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Product Details

  • Bioactivity

    MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM) .

  • Target

    LRRK2

  • Related Pathways

    Autophagy

  • CAS Number

    1627091-47-7

  • Purity

    0.9933

  • Molecular Formula

    C21H25N5O2

  • Molecular Weight

    379.46

  • SMILES

    C[C@H]1CN(C[C@@H](C)O1)c1cc(ncn1)-c1n[nH]c2ccc(OC3(C)CC3)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound