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Molfinity

MLS-0053105 - CAS 370572-36-4

MLS-0053105 - CAS 370572-36-4

MF-0110828-01

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Product Details

  • Bioactivity

    MLS-0053105, a chloromaleimide, functions as a selective inhibitor of BFL-1, exhibiting an IC50 of 0.4 μM against Bfl-1/F-Bid. Its inhibitory potency is over tenfold lower for Bcl-W, Bcl-2, and Bcl-XL, and it shows no activity against Bcl-B and Mcl-1.

  • Target

    Bcl-2 Family, FXR

  • Related Pathways

    Metabolism, Apoptosis

  • CAS Number

    370532

  • Molecular Formula

    C15H14Cl3N3O2

  • Molecular Weight

    374.65

  • SMILES

    O=C1C(Cl)=C(C(=O)N1C2=CC=C(Cl)C(Cl)=C2)N3CCN(C)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound