MM-401 TFA - CAS 1442106-11-7

MM-401 (TFA), an MLL1 H3K4 methyltransferase inhibitor, effectively impedes MLL1 activity (IC 50 = 0.32 μM) by preventing MLL1-WDR5 interaction. It can induce cell cycle arrest, apoptosis, and differentiation, offering potential for MLL leukemia research [1].

Others, Histone Methyltransferase, Apoptosis

Apoptosis, Others, Chromatin/Epigenetic

1442088

C31H47F3N8O7

700.75

C(C(O)=O)(F)(F)F.O=C1[C@H](NC(=O)[C@H](CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@](NC(C(C)C)=O)(C)CCCCN1)C2=CC=CC=C2

-20°C

Ice Packs

Small Compound