MMAF Hydrochloride - CAS 1415246-68-2

MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.

Microtubule Associated, ADC Cytotoxin

Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling

1415176

C39H66ClN5O8

768.42

Cl.[H][C@](NC(=O)[C@@H](NC)C(C)C)(C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O)OC

-20°C

Ice Packs

Small Compound