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Molfinity
MMAF-OtBu - CAS 745017-95-2
MMAF-OtBu - CAS 745017-95-2
SKU:MF-0095471-01
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Product Details
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Bioactivity
MMAF-OtBu (Example 2) is an OtBu-modified MMAF for synthesising ADCs (antibody-drug conjugates) . MMAF is an antitumour microtubule polymerisation inhibitor commonly employed as the cytotoxic component in ADCs.
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Target
Microtubule Associated, ADC Cytotoxin
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Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
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CAS Number
745017-95-2
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Purity
0.9894
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Molecular Formula
C43H73N5O8
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Molecular Weight
788.07
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SMILES
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC(C)(C)C)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@H](C(C)C)NC)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound