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Molfinity

MMV390048 - CAS 1314883-11-8

MMV390048 - CAS 1314883-11-8

SKU:MF-0033478-01

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  • Bioactivity

    MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM) . MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.

  • Target

    Parasite, PI4K

  • Related Pathways

    PI3K/Akt/mTOR signaling, Microbiology/Virology

  • CAS Number

    1314864

  • Purity

    0.9828

  • Molecular Formula

    C18H14F3N3O2S

  • Molecular Weight

    393.38

  • SMILES

    CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound