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MMV390048 - CAS 1314883-11-8
MMV390048 - CAS 1314883-11-8
SKU:MF-0033478-01
Regular price
$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM) . MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.
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Target
Parasite, PI4K
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Related Pathways
PI3K/Akt/mTOR signaling, Microbiology/Virology
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CAS Number
1314864
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Purity
0.9828
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Molecular Formula
C18H14F3N3O2S
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Molecular Weight
393.38
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SMILES
CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound