MMV666810 - CAS 1450666-97-3

MMV666810, a 2-aminopyrazine analogue of MMV390048, exhibits potent antiplasmodial activity against asexual parasites with an IC50 value of 5.94 nM. It demonstrates enhanced efficacy against late-stage gametocytes with a 3.3-fold higher selectivity relative to early stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM) .

Others, Parasite

Others, Microbiology/Virology

1450566

C23H21F3N4O2

442.43

NC=1C(=NC(=CN1)C2=CC=C(C(=O)N3CCC(O)CC3)C=C2)C4=CC=C(C(F)(F)F)C=C4

-20°C

Ice Packs

Small Compound