MNN-02-155 - CAS 3067681-22-2

MNN-02-155 is a bivalent molecular glue that can simultaneously interact with both p300/CBP and BCL6. It effectively induces the activation of BCL6-targeted reporter genes and promotes cell death. This compound is used in the research of diffuse large B-cell lymphoma (DLBCL) .

Histone Acetyltransferase, Bcl-6, Molecular Glues

Chromatin/Epigenetic, PROTAC, Immunology/Inflammation

3067657

C56H68ClF2N15O7

1136.69

O=C(NC)N1CC=2C(=NN(C2CC1)C3CCN(C(=O)CCCCNC(=O)C4CCN(C5=NC=C(Cl)C(=N5)NC=6C=C(OC)C7=C(C=C(OCC(=O)NC)C(=O)N7C)C6)CC4)CC3)N8C=9C=C(C(=CC9CCC8)C=%10C=NN(C%10)C)C(F)F

-20°C

Ice Packs

PROTAC