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MnTBAP chloride - CAS 55266-18-7
MnTBAP chloride - CAS 55266-18-7
SKU:MF-0152535
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Product Details
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Bioactivity
MnTBAP chloride (Mn (III) TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory effects through upregulation of BMPR-II and inhibition of NFκB signaling. mnTBAP chloride is a manganese porphyrin complex with antioxidant properties and has potential for use in the study of fibrotic responses in chronic kidney diseases (CKDs) .
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Target
Antioxidant, NF-κB
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Related Pathways
NF-κB, Oxidation-Reduction
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CAS Number
55241
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Molecular Formula
C48H25ClMnN4O8
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Molecular Weight
876.13
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SMILES
[H+].O=C([O-])C=1C=CC(=CC1)C2=C3C=CC=4C(C=5C=CC(=CC5)C(=O)[O-])=C6C=CC7=C(C8=CC=C(C=C8)C(=O)[O-])C=9C=CC%10=C(C%11=CC=C(C=C%11)C(=O)[O-])C%12=CC=C2[N-]%12[Mn+3]([Cl-])([N]34)([N]%109)[N-]67
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound