Mofarotene - CAS 125533-88-2

Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tumors and respiratory diseases.Mofarotene is a retinoic acid analog that binds to and activates retinoic acid receptors (RARs), which alters the expression of certain genes, leading to reduced cell differentiation and cell proliferation in susceptible cells.

ROS, Reactive Oxygen Species, Apoptosis, Caspase, Retinoid Receptor

Immunology/Inflammation, Metabolism, NF-κB, Proteases/Proteasome, Apoptosis

125443

0.9996

C29H39NO2

433.63

CC1(C)C=2C(C(C)(C)CC1)=CC=C(\C(=C\C3=CC=C(OCCN4CCOCC4)C=C3)\C)C2

-20°C

Ice Packs

Small Compound