Monascuspiloin - CAS 1011244-19-1

Monascuspiloin (Monascinol), a compound extracted from rice fermented with Rhodobacter sphaeroides, exhibits antiandrogenic and antitumor activity and inhibits the proliferation of PC-3 and LNCaP.Monascuspiloin improves lipid metabolism and hepatic function in over-alcohol-addicted mice by decreasing hepatic MDA levels and increasing hepatic CAT, SOD and GSH levels.Monascuspiloin has been shown to improve lipid metabolism and hepatic function in over-alcoholized mice. Monascuspiloin regulates the transcription and protein expression of genes related to hepatic lipid metabolism and oxidative stress, and can be used to study alcohol-induced liver injury.

AMPK, Autophagy, mTOR, Apoptosis, Akt, Androgen Receptor

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis, Autophagy, Endocrinology/Hormones, Chromatin/Epigenetic

1011244-19-1

C21H28O5

360.44

C[C@]12[C@@]([C@@H]([C@H](CCCCC)O)C(=O)O1)(CC3=C(C2=O)COC(/C=C/C)=C3)[H]

-20°C

Ice Packs

Natural Product