Monoamine Oxidase B inhibitor 4 - CAS 424794-91-2

Monoamine Oxidase B Inhibitor 4 (compound 1l), with a potent IC50 value of 8.3 nM, is a selective human monoamine oxidase-B (hMAO-B) inhibitor. This compound demonstrates anti-neuroinflammatory properties and exhibits low neurotoxicity. It effectively inhibits the release of NO, TNF-α, and IL-1β induced by LPS and Aβ1-42, and additionally mitigates the cytotoxic effects triggered by Aβ (1-42) .

Monoamine Oxidase

Neuroscience

424794-91-2

C15H11Cl2NO3

324.16

O=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=C3OCCOC3=C2

-20°C

Ice Packs

Small Compound