Monohydroxy Melphalan hydrochloride - CAS 2707535-88-2

Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 μg/ml.

Others, Drug Metabolite

Metabolism, Others

2707535-88-2

C13H19ClN2O3?2HCl

359.68

N(CCCl)(CCO)C1=CC=C(C[C@@H](C(O)=O)N)C=C1.Cl

-20°C

Ice Packs

Small Compound