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Molfinity

Monomethyl auristatin E - CAS 474645-27-7

Monomethyl auristatin E - CAS 474645-27-7

SKU:MF-0050850-01

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  • Bioactivity

    Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.

  • Target

    Apoptosis, ADC Cytotoxin, Microtubule Associated

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

  • CAS Number

    474611

  • Purity

    0.999

  • Molecular Formula

    C39H67N5O7

  • Molecular Weight

    717.98

  • SMILES

    CC[C@H](C)C([C@@H](CC(=O)N1CCC[C@H]1C(OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)[C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC