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Monomethyl auristatin E - CAS 474645-27-7
Monomethyl auristatin E - CAS 474645-27-7
SKU:MF-0050850-01
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$40.65 USD
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$40.65 USD
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Product Details
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Bioactivity
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
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Target
Apoptosis, ADC Cytotoxin, Microtubule Associated
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Related Pathways
Apoptosis, Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
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CAS Number
474611
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Purity
0.999
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Molecular Formula
C39H67N5O7
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Molecular Weight
717.98
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SMILES
CC[C@H](C)C([C@@H](CC(=O)N1CCC[C@H]1C(OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)[C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC)C(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC