MOR-106 - CAS 2304625-87-2

MOR-106 (MOR12743) is a humanized anti-IL-17C IgG1 monoclonal antibody. It works by specifically binding to IL-17C, thereby inhibiting the NF-κB signaling pathway, with an IC50 of 59 pM for human IL-17C and 55 pM for mouse IL-17C. MOR-106 effectively reduces skin inflammation and related inflammatory factors in animal models of psoriasis and atopic dermatitis.

Interleukin, NF-κB

Immunology/Inflammation, NF-κB

2304625-87-2

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Ice Packs

Inhibitory Antibodies