MOR modulator-1 - CAS 2976336-81-7

MOR modulator-1 (compound 6) is a potent and selective modulator of the μ opioid receptor (MOR) . Compared to NAT (6α-configuration), MOR modulator-1 demonstrates improved opioid receptor selectivity, enhanced antagonistic effects in vivo, and overall reduced withdrawal symptoms. It connects to the μ, δ, and γ receptors with carboxamide linkers, showing Ki values of 0.25, 41.1, and 1.30 nM respectively.

Opioid Receptor

Neuroscience, GPCR/G Protein, Endocrinology/Hormones

2976248

C24H27N3O4S

453.554

O[C@]12[C@@]34C=5C(O[C@]3([C@@H](NC(=O)C6=NC=CS6)CC1)[H])=C(O)C=CC5C[C@]2(N(CC7CC7)CC4)[H]

-20°C

Ice Packs

Small Compound