Morachalcone A - CAS 76472-88-3

Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM) ; it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells against glutamate-induced oxidative stress, with EC50 values of 35.5±2.1 uM. It exhibits potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC50 value of 16.4 microM.

Tyrosinase, NO Synthase

Immunology/Inflammation, Proteases/Proteasome

76381

0.97

C20H20O5

340.37

C\C(C)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O

-20°C

Ice Packs

Natural Product