Moracin M - CAS 56317-21-6

Moracin M, a phenolic compound found in the skin of Morus alba Linn., effectively inhibits phosphodiesterase-4 (PDE4), exhibiting IC50 values of 2.9 μM and 4.5 μM for PDE4D2 and PDE4B2, respectively, and showing significantly lesser activity on PDE5A1 and PDE9A2 with values over 40 μM and 100 μM, respectively. This compound demonstrates notable anti-inflammatory activity.

Endogenous Metabolite, PDE, NF-κB, Autophagy

Autophagy, NF-κB, Metabolism

56290

0.9986

C14H10O4

242.23

Oc1ccc2cc(oc2c1)-c1cc(O)cc(O)c1

-20°C

Ice Packs

Natural Product