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MORINDONE - CAS 478-29-5
MORINDONE - CAS 478-29-5
SKU:MF-0111921-01
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Product Details
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Bioactivity
MORINDONE, an anthraquinone compound, exhibits significant binding affinity towards multiple targets including β-catenin, MDM2-p53, and KRAS. It displays notable cytotoxicity and selective activity against colorectal cancer cell lines, and effectively downregulates the expression of mutated TP53 and KRAS genes.
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Target
Ras, Kras
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Related Pathways
MAPK
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CAS Number
444
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Molecular Formula
C15H10O5
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Molecular Weight
270.24
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SMILES
O=C1C2=CC=C(C(O)=C2C(=O)C3=CC=C(O)C(O)=C13)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound