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Motexafin gadolinium - CAS 246252-06-2
Motexafin gadolinium - CAS 246252-06-2
SKU:MF-0045367
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Motexafin gadolinium, also known as PCI 0120, is a synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy.
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Target
Others
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Related Pathways
Others
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CAS Number
246252-06-2
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Molecular Formula
C52H72GdN5O14
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Molecular Weight
1148.42
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SMILES
CCC1=C2[N-]3[Gd+3]456([N](c7c([N]4=CC4=[N]5C(=CC3=C1CC)C(CCCO)=C4C)cc(c(c7)OCCOCCOCCOC)OCCOCCOCCOC)=CC1=[N]6C(=C2)C(CCCO)=C1C)([O-]C(=O)C)[O-]C(=O)C |c:10,12,15,18,27,57,59,62,69,t:2,^1:4,6,9,12,54|
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound