MPGES1-IN-4 - CAS 2253745-78-5

MPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.

Others, PGE Synthase

Others, Immunology/Inflammation

2253662

C27H25F2N3O

445.5

FC=1C(F)=C(C=CC1OCC=2C=CC=CC2)C=3N=C(N=C(C=4C=CC=CC4)C3CCCC)N

-20°C

Ice Packs

Small Compound