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MPGES1-IN-5 - CAS 2253745-70-7
MPGES1-IN-5 - CAS 2253745-70-7
SKU:MF-0142590-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
MPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.
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Target
Others, PGE Synthase
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
2253668
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Molecular Formula
C27H27N3O
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Molecular Weight
409.52
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SMILES
N=1C(=NC(C=2C=CC(OCC=3C=CC=CC3)=CC2)=C(C1C=4C=CC=CC4)CCCC)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound