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MPO-IN-4 - CAS 2088545-68-8
MPO-IN-4 - CAS 2088545-68-8
SKU:MF-0047674-01
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Product Details
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Bioactivity
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC50 of 25 nM and also demonstrates inhibition of thyroid peroxidase (TPO) with an IC50 of 2.2 μM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT) [1].
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Target
Others, Glutathione Peroxidase
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Related Pathways
Metabolism, Others
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CAS Number
2088469
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Molecular Formula
C12H11N5
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Molecular Weight
225.25
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SMILES
C(C1=C2C(=NC(N)=C1)N=NN2)C3=CC=CC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound