Mps1-IN-1 dihydrochloride - CAS 1883548-93-3

Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM. It effectively inhibits the activity of Mps1 mitotic kinase and disrupts spindle assembly checkpoint (SAC) function, thereby reducing the viability of both cancerous and 'normal' cells.

Kinesin, Others

Cytoskeletal Signaling, Others

1883452

C28H35Cl2N5O4S

608.58

Cl.Cl.O=S(=O)(C=1C=CC=CC1NC=2C=C(N=C3NC=CC32)NC4=CC=C(C=C4OC)N5CCC(O)CC5)C(C)C

-20°C

Ice Packs

Small Compound