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Molfinity

MPT0G211 - CAS 2151853-97-1

MPT0G211 - CAS 2151853-97-1

MF-0006983-01

$104.63 USD
$63.70 USD $104.63 USD
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Product Details

  • Bioactivity

    MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human breast cancer cells. MPT0G211 has 1,000 times more affinity for HDAC6 than other HDAC subtypes. MPT0G211 can cross the blood-brain barrier and could be used to improve tau phosphorylation and cognitive deficits in Alzheimer's disease models.

  • Target

    HDAC

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    2151853-97-1

  • Purity

    0.9998

  • Molecular Formula

    C17H15N3O2

  • Molecular Weight

    293.32

  • SMILES

    ONC(=O)c1ccc(CNc2cccc3cccnc23)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound