MR2938 - CAS 1044870-65-6

MR2938 is a potent acetylcholinesterase (AChE) inhibitor, evidenced by an IC50 value of 5.04 μM, and significantly inhibits nitric oxide (NO) production with an IC50 of 3.29 μM. Additionally, it mitigates neuroinflammation by blocking the MAPK/JNK and NF-κB signaling pathways, making it a promising compound for Alzheimer's disease (AD) research.

JNK, NF-κB, Cholinesterase (ChE), NOD-like Receptor (NLR), Others, CCR, Interleukin, TNF, NO Synthase

Apoptosis, Microbiology/Virology, GPCR/G Protein, Others, NF-κB, Immunology/Inflammation, Neuroscience, MAPK

1044799

C21H24N4O3

380.44

O(C)C1=C2C(NC(=NC2=O)C3=CC=C(C=C3)N4CCN(C)CC4)=CC(OC)=C1

-20°C

Ice Packs

Small Compound