MrgprX2-IN-1 - CAS 2792202-91-4

MrgprX2-IN-1 (Compound 2-10) is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) . It functions by inhibiting mast cell degranulation and the release of inflammatory mediators mediated by MRGPRX2, thereby blocking non-IgE-dependent immune responses. MrgprX2-IN-1 holds potential for research into pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.

MRGPR

GPCR/G Protein

2792107

C22H21F3N6O

442.44

N(C=1N2C(=NC(C(F)(F)F)=C2)C=CC1)[C@@H]3CC[C@H](NC(=O)C4=C5C(C=NN5)=CC=C4)CC3

-20°C

Ice Packs

Small Compound