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Molfinity
MRIA9 - CAS 2750707-05-0
MRIA9 - CAS 2750707-05-0
SKU:MF-0037449-01
Regular price
$574.75 USD
Regular price
$388.70 USD
Sale price
$574.75 USD
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Product Details
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Bioactivity
MRIA9, an ATP-competitive inhibitor targeting pan Salt-Inducible Kinases (SIK) and PAK2/3, demonstrates IC50 values of 516 nM, 180 nM, and 127 nM for SIK1, SIK2, and SIK3, respectively [1].
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Target
Others, PAK, Apoptosis, SIK
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Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling
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CAS Number
2750707-05-0
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Molecular Formula
C24H22ClFN6O3
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Molecular Weight
496.92
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SMILES
C(N1C=2C(C=C(C1=O)C3=C(Cl)C=C(C=C3)C4=C(F)C=CC=N4)=CN=C(NC)N2)[C@@H]5OC[C@@H](N)CO5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound