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Molfinity

MRK-016 - CAS 342652-67-9

MRK-016 - CAS 342652-67-9

MF-0017981-01

$41.39 USD
$41.39 USD
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Product Details

  • Bioactivity

    MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, (IC50=3 nM) with the advantages of being orally available and penetrating the blood-brain barrier.MRK-016 increases long time period potentiation (LTP) in mouse hippocampal slices, with memory-improvement, antidepressant, and pain-treating effects.

  • Target

    GABA Receptor

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience

  • CAS Number

    342576

  • Purity

    0.9976

  • Molecular Formula

    C17H20N8O2

  • Molecular Weight

    368.39

  • SMILES

    N=1N=C(C2=NOC(=C2)C)N3N=C(OCC4=NC=NN4C)C(=C3C1)C(C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound