MRK-623 - CAS 461449-78-5

MRK-623 (Compound 14k) is a potent, orally active agonist of the GABA A receptor with high affinity for subunits α1, α2, α3, and α5, exhibiting Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM, respectively. Notably, MRK-623 demonstrates anxiolytic effects [1].

Others, GABA Receptor

Neuroscience, Membrane transporter/Ion channel, Others

461366

C20H17FN4O

348.37

C(C)(C)(O)C1=NC=2N(C(=CN2)C3=CC(=C(F)C=C3)C=4C=CC=NC4)C=C1

-20°C

Ice Packs

Small Compound