MRS 1523 - CAS 212329-37-8

MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 nM for human and rat A3 receptors, respectively) . In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively.

Calcium Channel, Adenosine Receptor, Others

GPCR/G Protein, Metabolism, Neuroscience, Others, Membrane transporter/Ion channel

212284

C23H29NO3S

399.55

CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c1ccccc1

-20°C

Ice Packs

Small Compound