MRS5663 - CAS 1377272-66-6

MRS5663 (Compound 3a), an A3AR agonist, exhibits an EC50 value of 5.62 nM in β-arrestin2 recruitment assays. This compound demonstrates cytoprotective effects in skeletal muscle ischemia-reperfusion injury/claudication models.

Adenosine Receptor

GPCR/G Protein, Neuroscience

1377272-66-6

C22H21ClN6O3

452.89

C(NC)(=O)[C@]12[C@](C1)([C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(NC)N=C(C#CC5=C(Cl)C=CC=C5)N4)[H]

-20°C

Ice Packs

Small Compound