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Molfinity

MRT-23227 - CAS 3050683-03-6

MRT-23227 - CAS 3050683-03-6

MF-0118884-01

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Product Details

  • Bioactivity

    MRT-23227 is a molecular glue degrader targeting cereblon (CRBN) . It forms a ternary complex with CRBN and G3BP2, which activates the ubiquitin-proteasome system to degrade G3BP2. MRT-23227 shows potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.

  • Target

    Molecular Glues

  • Related Pathways

    PROTAC

  • CAS Number

    3050683-03-6

  • Molecular Formula

    C22H20ClN3O3

  • Molecular Weight

    409.87

  • SMILES

    O=C1NC(=O)C(C=2C=CC=C(C=3C=CC(OCC4=NN(C=C4)C)=CC3)C2Cl)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC