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MRTX1133 - CAS 2621928-55-8

MRTX1133 - CAS 2621928-55-8

SKU:MF-0014067-01

Regular price $222.87 USD
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  • Bioactivity

    MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.

  • Target

    Ras, Kras

  • Related Pathways

    MAPK, GPCR/G Protein

  • CAS Number

    2621865

  • Purity

    0.996

  • Molecular Formula

    C33H31F3N6O2

  • Molecular Weight

    600.63

  • SMILES

    Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(C#C)c(F)ccc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound