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MRTX1133 - CAS 2621928-55-8
MRTX1133 - CAS 2621928-55-8
SKU:MF-0014067-01
Regular price
$222.87 USD
Regular price
Sale price
$222.87 USD
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Product Details
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Bioactivity
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
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Target
Ras, Kras
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Related Pathways
MAPK, GPCR/G Protein
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CAS Number
2621865
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Purity
0.996
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Molecular Formula
C33H31F3N6O2
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Molecular Weight
600.63
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SMILES
Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(C#C)c(F)ccc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound