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Molfinity

MS21 - CAS 2376137-05-0

MS21 - CAS 2376137-05-0

MF-0152803

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.

  • Target

    Ras, PROTACs, Akt, Kras

  • Related Pathways

    PROTAC, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, MAPK

  • CAS Number

    2376137-05-0

  • Molecular Formula

    C58H79ClN12O6S

  • Molecular Weight

    1107.86

  • SMILES

    Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCC(=O)N2CCN(CC[C@H](NC(=O)C3(N)CCN(CC3)c3ncnc4[nH]ccc34)c3ccc(Cl)cc3)CC2)C(C)(C)C)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC