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Molfinity

MSA-2 - CAS 129425-81-6

MSA-2 - CAS 129425-81-6

MF-0018814-01

$35.41 USD
$35.41 USD
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Product Details

  • Bioactivity

    MSA-2 is an orally available non-nucleotide STING agonist. The non-covalent dimer of MSA-2 binds to STING with nanomolar affinity. It shows anti-tumor activity in syngeneic mouse tumor models, synergizes with anti-PD-1, stimulates tumor secretion of interferon-β, induces tumor regression, and has long-lasting anti-tumor immunity. [3]

  • Target

    STING

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    129338

  • Purity

    0.9888

  • Molecular Formula

    C14H14O5S

  • Molecular Weight

    294.32

  • SMILES

    COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound