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MSA-2 dimer - CAS 2377881-92-8
MSA-2 dimer - CAS 2377881-92-8
SKU:MF-0152471
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Product Details
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Bioactivity
MSA-2 dimer, a selective and orally active non-nucleotide STING agonist with a dissociation constant (Kd) of 145 μM, demonstrates prolonged antitumor and immunogenic activity. It non-covalently binds to STING as a dimer, showing greater permeability compared to cyclic dinucleotide[1].
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Target
Others, STING
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
2377781
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Molecular Formula
C29H28O8S2
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Molecular Weight
568.66
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SMILES
COc1cc2sc(cc2cc1CCCc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O)C(=O)CCC(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound