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MSC 2032964A - CAS 1124381-43-6
MSC 2032964A - CAS 1124381-43-6
SKU:MF-0019694-01
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$66.81 USD
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$66.81 USD
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Product Details
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Bioactivity
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
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Target
ASK, p38 MAPK, MAPK
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Related Pathways
MAPK, Apoptosis
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CAS Number
1124332
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Purity
>99.99%
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Molecular Formula
C16H13F3N6O
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Molecular Weight
362.31
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SMILES
FC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound