MSIRK - CAS 593267-11-9

MSIRK (G-Protein βγ Binding Peptide) is a cell-permeable activator of ERK 1/2 with an EC50 of 2.5-5 μM. It disrupts the interaction between the α and βγ subunits, facilitating α subunit dissociation without inducing nucleotide exchange [1].

ERK

MAPK

593247

0.9926

C93H150N20O25

1948.31

C([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CO)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCCN)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)CC(O)=O)=O)CCC2

-20°C

Ice Packs

Peptide