MSU-42011 - CAS 2456434-36-7

MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.

NOS, Retinoid Receptor, Ras, Lipid, Kras, PERK, NO Synthase

Apoptosis, Metabolism, Immunology/Inflammation, MAPK

2456391

0.996

C24H34N2O2

382.54

N(CC(C)C)(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)C2=CC=C(C(O)=O)C=N2

-20°C

Ice Packs

Small Compound