MT-1207 - CAS 1610794-70-1

MT-1207 is a selective antagonist of adrenergic α1 and 5-HT2A receptors with oral activity. It exhibits IC50 values of <0.1 nM for α1A, 0.15 nM for α1B, 1.40 nM for α1D, and 0.27 nM for 5-HT2A. In the 2K2C rat model, MT-1207 effectively reduces blood pressure (BP) without impairing renal function. As a multitarget inhibitor, MT-1207 has potential for research in vasodilation.

5-HT Receptor, Adrenergic Receptor

Neuroscience, GPCR/G Protein

1610794-70-1

C21H25ClN6S

428.98

Cl.N1=NN(C=2C=CC=CC12)CCCCN3CCN(C4=NSC=5C=CC=CC54)CC3

-20°C

Ice Packs

Small Compound