Mt KARI-IN-2 - CAS 2413974-52-2

Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].

Others, Antibacterial

Microbiology/Virology, Others

2413920

C14H11N5O4S2

377.4

N(C(NC1=CC=C(OC)C=C1)=S)C=2SC(=NN2)C=3OC(N(=O)=O)=CC3

-20°C

Ice Packs

Small Compound