Mt KARI-IN-4 - CAS 2413974-53-3

Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki of 5.48 μM. It also inhibits Mtb H37Rv, displaying a minimum inhibitory concentration (MIC) of 0.78 μM, and exhibits low cytotoxicity, with an IC50 over 72 μg/mL against human embryonic kidney cells (HEK) [1].

Others, Antibacterial

Others, Microbiology/Virology

2413918

C13H8FN5O3S2

365.36

N(C(NC1=CC=C(F)C=C1)=S)C=2SC(=NN2)C=3OC(N(=O)=O)=CC3

-20°C

Ice Packs

Small Compound