MTH1 activator-1 - CAS 2803422-60-6

MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

2803356

C29H23F3N4O2

516.514

O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCOCC2)C3=NC=C(C#CC4=CC=CC=5C=NC=CC45)C=C3

-20°C

Ice Packs

Small Compound