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MTI-31 - CAS 1567915-38-1
MTI-31 - CAS 1567915-38-1
SKU:MF-0043531-01
Regular price
$222.87 USD
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$222.87 USD
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Product Details
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Bioactivity
MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2, exhibiting a Kd of 0.20 nM for mTOR and >5,000-fold selectivity over PIK3CA, PIK3CB, and PIK3G in binding assays, with an IC50 of 39 nM for mTOR in a LANCE assay of mTOR substrate phosphorylation with 100 μM ATP [1].
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Target
MTOR
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Related Pathways
PI3K/Akt/mTOR signaling
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CAS Number
1567876
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Purity
0.9997
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Molecular Formula
C26H30N6O3
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Molecular Weight
474.55
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SMILES
CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound