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Molfinity

MTI-31 - CAS 1567915-38-1

MTI-31 - CAS 1567915-38-1

SKU:MF-0043531-01

Regular price $222.87 USD
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  • Bioactivity

    MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2, exhibiting a Kd of 0.20 nM for mTOR and >5,000-fold selectivity over PIK3CA, PIK3CB, and PIK3G in binding assays, with an IC50 of 39 nM for mTOR in a LANCE assay of mTOR substrate phosphorylation with 100 μM ATP [1].

  • Target

    MTOR

  • Related Pathways

    PI3K/Akt/mTOR signaling

  • CAS Number

    1567876

  • Purity

    0.9997

  • Molecular Formula

    C26H30N6O3

  • Molecular Weight

    474.55

  • SMILES

    CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound